Prevalence of Diabetes Mellitus among Patients with Chronic Liver Disease in a Tertiary Care Centre

Authors

  • Parimal Koirala Department of Internal Medicine, National Academy of Medical Sciences, Bir Hospital, Mahaboudha, Kathmandu, Nepal. https://orcid.org/0000-0001-5538-7394
  • Binod Pantha Department of Internal Medicine, National Academy of Medical Sciences, Bir Hospital, Mahaboudha, Kathmandu, Nepal.
  • Milan Khadka Department of Internal Medicine, National Academy of Medical Sciences, Bir Hospital, Mahaboudha, Kathmandu, Nepal.
  • Lochan Karki Department of Internal Medicine, National Academy of Medical Sciences, Bir Hospital, Mahaboudha, Kathmandu, Nepal.

DOI:

https://doi.org/10.56974/pmjn.231

Keywords:

child-pugh score, chronic liver disease, diabetes mellitus.

Abstract

Introduction: Diabetes mellitus is a metabolic disease characterized by impaired blood glucose regulation and altered insulin sensitivity. Diabetes mellitus has a high risk of microvascular or macrovascular complications, thus reducing life expectancy, impaired quality of life, and significant morbidity. The prevalence of diabetes is higher in patients who have liver diseases. This study aimed to find out the prevalence of diabetes mellitus among patients with chronic liver disease.

Methods: A descriptive cross-sectional study was conducted among participants diagnosed with diabetes mellitus at the Department of Internal Medicine in a tertiary care centre after obtaining the ethical approval from the Institutional Review Board. Patients with chronic liver disease irrespective of gender fulfilling the inclusion criteria were enrolled in the study. Data was collected and analyzed using IBM SPSS Statistics version 27. Convenience sampling method was used. Point prevalence and 90% Confidence Interval were calculated.

Results: Among 45 patients with chronic liver disease, the prevalence of diabetes mellitus was present in 10 (22.2%) [12.03 32.42, 90% Confidence Interval]. The frequency of diabetes mellitus in chronic liver disease patients was highest in chronic hepatitis C-related liver cirrhosis. Child-Pugh score C had the highest frequency for diabetes mellitus occurrence 9 (20%) compared to Child-Pugh A and B.

Conclusions: The prevalence of diabetes mellitus among patients with chronic liver disease was found to be similar to other studies done in similar settings.

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Published

2024-03-31

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Section

Original Articles