Organophosphate Induced Delayed Neuropathy: A Case Report

Abstract

Organophosphate-induced delayed neuropathy (OPIDN) is an uncommon toxicity usually occurring in 1-3 weeks following exposure to certain organophosphorus (OP) compounds. It is characterized by distal symmetric sensory-motor polyneuropathy (weakness, paraesthesia, ataxia, diminished or absent reflexes). We describe a 22 years-old female patient who developed cholinergic crisis after initial exposure and later developed paraesthesia associated with lower limbs paresis six weeks after she had ingested a Chlorpyriphos-based insecticide. Nerve conduction Study demonstrated an axonal polyneuropathy pattern.