The Impact of Obesity on the Course and Outcome of Acute Pancreatitis

Mishra U*, Thapa G,* Gurung K,*

Abstract


Body overweight and obesity have been associated with an increased morbidity in acute pancreatitis, but conflicting results were reported in the literature with regard to the type and frequency of complications. We investigated the occurrence of complications in different classes of overweight in a homogeneous group of patients with gallstone pancreatitis.

Method: Seventy-two patients admitted for pancreatitis were prospectively studied in Bir Hospital from june 2012 to September 2013. Patients were classified as underweight (BMI < 18.9 kg/
m2), of normal weight (18.9-24.9 kg/m2), overweight (24.9-29.9 kg/m2) or obese (>30 kg/m2). General data, AP etiology, admission AP prognostic criteria, and occurrence of complications were recorded in each categories. The outcome for each category was measured by the components of the Atlanta criteria. Secondary end points of the study were the length of hospital stay, the length of stay at the intensive care unit, and the number of abdominal operations.
Result: Prevalence of obesity was 34.7%. When compared with normal-weight patients (BMI 18.5- 24.9), the categories with BMI >25 had an increased risk of developing the severe form
of acute pancreatitis Patients with obesity (BMI > 30) developed significantly more systemic complications (28.5% versus 0%) and local complications(76% versus 11.7%) than non-obese
(BMI 24.9-29-9). They needed also more frequently intensive care and had a longer total hospital stay. There was no mortality.
Conclusion: In acute pancreatitis, body overweight and obesity represent a risk of more severe disease and the number and type of complications increase in categories of increasing BMI.

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