Biochemical Profile in Xanthelasma Palpebrarum

Ghimire S*, Kayastha BMM**

Abstract


INTRODUCTION: Xanthomas occurring over eyelids are Xanthelasma Palpebrarum (XP) and are one of the important cutaneous manifestations of hyperlipedimia, atherosclerosis, and coronary heart disease. The hyperlipedimia and obesity are also found interrelated but there are very limited literatures regarding
these problem and xanthelasma palpebrarum. This study was carried out to find out the clinical relationship between xanthelasma and biochemical profile.

METHOD: This was the hospital based cross sectional study which was approved by institutional review board (IRB). In total forty two patients were included in the study once the clinical diagnosis was made and biochemical profile was investigated after taking informed consent. Findings were tabulated and analyzed by
using statistical tool SPSS.

RESULT: In total forty two patients were included in the study. Forty seven percent of the cases were in the age group of 31 – 55 years. XP was found in thirteen patients who were below 30 years of age. And it was more common (78.6 %) in female and non-vegetarian (81.3%). Fifty percent of the patient had high level of
triglycerides and twenty six percent of patients had increased level of cholesterol. Twelve percent were obese and forty percent had BMI between 18.6 to 24.9.

CONCLUSION: Young married and non-vegetarian populations are at higher risk of having Xanthelasma palpebrarum. Lipid profile and BMI was not significantly increased in every cases of XP.

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