Pathological Correlation of Solid Liver Lesion with Gray Scale Sonographic Findings

Thakur A Jha AK, Koirala KB,


Wide availability, high sensitivity and low cost make ultrasound the preferred modality in imaging of abdomen and in particular the liver. Radiologists need to identify lesions as well as to characterize the malignant ones that need biopsy since it is not possible to biopsy all liver lesions. The objective of study was to analyse the sonographic findings of a focal solid liver lesion with an attempt to differentiate malignant from benign hepatic lesions. The study was a prospective, hospital-based observational study carried out in the radiology department of Bir Hospital from April 2013 to April 2014. Total of 50 patients from age >/= 15 years referred for USG of abdomen with suspicious solid lesion in liver were included in the study. All cases with a solid liver lesion were evaluated for site, size, number, echogenicity, margin, hypoechoic halo and calcification on B-mode USG &categorised into benign & malignant types. They underwent FNAC based pathological diagnosis. Correlations were obtained between sonographic and pathologic findings. Data analysis was done using SPSS 21.0 and MS-Excel Software. Chi Square test was used for statistical analysis. In our study of 50 patients, grey scale prediction of malignancy had a sensitivity of 97%, specificity of 66%, PPV of 93%, NPV of 85% and Accuracy of 92%. Thus we concluded that ultrasonography is a useful modality to detect and differentiate benign from malignant solid liver lesion. It can minimize the unnecessary biopsy in benign lesion. 4

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